RNA aptamer evaluation using comparative molecular interaction profile analysis system.

نویسندگان

  • Yoshiharu Hayashi
  • Satoshi Takahashi
  • Katsuyoshi Sakaguchi
  • Nao Iwata
  • Masaki Kobayashi
چکیده

In this paper, we introduce a system named Comparative Molecular Interaction Profile Analysis system (CoMIPA) that utilizes virtual docking study for comprehensive analysis of molecular interactions. Research of RNA aptamer is very useful to creation of functional molecules, because RNA aptamer is excellent in binding selectivity and the stability of structure. By using 3-bases RNA fragment, the system can use computational molecular docking results to help for RNA aptamer screening. We believe that the system has the potential to be a useful for RNA aptamer design.

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عنوان ژورنال:
  • Nucleic acids research. Supplement

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2003